Some of life’s greatest moments come with uncontrollable movements – throwing your hands in the air when
your team makes a big play, dancing happily to your favorite song, laughing until you can’t breathe. But
for someone with tardive dyskinesia, uncontrollable movements have an entirely different meaning.
Tardive dyskinesia can be caused by long-term use of drugs called dopamine receptor blocking agents, which
can include drugs used to treat psychiatric and mood disorders. The condition is characterized by sudden,
uncontrollable movements including:
- Movement of the lips and tongue (grimacing, smacking, pursing, fish-like movements, sticking out the tongue)
- Rapid blinking
- Impaired finger movement or "fluttering"
- Rapid arm movements
- Toe tapping or moving the leg up and down
- Twisting and bending of the torso (in severe cases)
While there is no cure for the condition, a medication called valbenazine (or INGREZZA®) was approved by
the United States Food and Drug Administration in April 2017 for the treatment of adults with tardive
dyskinesia. Clinical research studies are being conducted to gather more information on the safety,
tolerability, and effectiveness of valbenazine, and you may be able to take part.